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Tetrathiomolybdate

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Drug Profile

Tetrathiomolybdate

Alternative Names: ATN-224 analogue; Coprexa; TTM

Latest Information Update: 14 Oct 2022

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At a glance

  • Originator University of Michigan
  • Developer Theriva Biologics
  • Class Heavy metals; Small molecules
  • Mechanism of Action Amyloid beta-protein precursor inhibitors; Chelating agents; Fibroblast growth factor inhibitors; Transforming growth factor beta inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Pulmonary fibrosis
  • New Molecular Entity Yes

Highest Development Phases

  • Suspended Alzheimer's disease; Hepatolenticular degeneration; Huntington's disease; Primary biliary cirrhosis; Pulmonary fibrosis

Most Recent Events

  • 12 Oct 2022 Synthetic Biologics is now called Theriva Biologics
  • 16 Feb 2012 Adeona Pharmaceuticals is now called Synthetic Biologics
  • 02 Sep 2009 Adeona Pharmaceuticals is seeking partners for further development of Tetrathiomolybdate (http://www.adeonapharma.com/)

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