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Drug Profile


Alternative Names: 4'-Thio-Ara-C; 4-thio Ara-C; GS 7836; OSI 7836; SR 9025; T-araC; Thiocytosine arabinoside; VP700 series; VP701

Latest Information Update: 18 Sep 2015

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At a glance

  • Originator Southern Research Institute
  • Developer Abeona Therapeutics
  • Class Antineoplastics; Arabinonucleosides; Small molecules
  • Mechanism of Action DNA synthesis inhibitors; Immunomodulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Discontinued Leukaemia; Rheumatoid arthritis

Most Recent Events

  • 28 Feb 2011 Phase-I development is ongoing in USA
  • 07 Jul 2009 Pharmacodynamics data from preclinical trials in Rheumatoid arthritis released by Access Pharmaceuticals
  • 04 Jun 2009 Pharmacodynamics data from a Preclinical trial in Cancer released by Access Pharmaceuticals
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