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Valproate semisodium - Abbott Laboratories

Drug Profile

Valproate semisodium - Abbott Laboratories

Alternative Names: [14C]-Sodium Valproate; Depakote; Depakote ER; Divalproex; Divalproex sodium; Divalproex sodium DR 500mg tablets - Abbott Laboratories; Epival; Epival ER; LA40220

Latest Information Update: 27 May 2019

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At a glance

  • Originator Abbott Laboratories
  • Developer Abbott Laboratories; Sanofi
  • Class Antiepileptic drugs; Antimanics; Antimigraines; Pentanoic acids; Small molecules
  • Mechanism of Action Enzyme inhibitors; GABA agents; GABA modulators; Voltage-gated sodium channel modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Bipolar disorders; Epilepsy; Migraine
  • Phase III Dementia

Most Recent Events

  • 11 Apr 2019 Sanofi completes a phase I trial in Epilepsy (In volunteers) in United Kingdom (PO) (NCT03681158)
  • 02 Nov 2018 Phase-I clinical trials in Epilepsy (In volunteers) in United Kingdom (PO) (NCT03681158)
  • 28 Sep 2018 Sanofi plans a phase I BEX15316 trial for Epilepsy (In volunteers) in Canada and USA (PO) in November 2018 (NCT03681158) (EudraCT2017-004987-36)
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