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ATL 1102

Drug Profile

ATL 1102

Alternative Names: ATL-1102; ATL/TV-1102; ISIS-107248; TV-1102

Latest Information Update: 28 May 2020

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At a glance

  • Originator Isis Pharmaceuticals
  • Developer Antisense Therapeutics; Childrens Hospital Los Angeles
  • Class Anti-inflammatories; Antineoplastics; Antirheumatics; Antisense oligonucleotides
  • Mechanism of Action Integrin alpha4 inhibitors; Integrin alpha4beta1 antagonists; RNA inhibitors; RNA interference
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes - Asthma; Multiple sclerosis

Highest Development Phases

  • Phase II Duchenne muscular dystrophy; Multiple sclerosis
  • No development reported Asthma; Cancer
  • Discontinued Stem cell mobilisation; Vertigo

Most Recent Events

  • 21 May 2020 Antisense Therapeutics anticipates Scientific Guidance from EMA for its planned phase IIb trial in Duchenne muscular dystrophy in Europe and United Kingdom in mid-2020
  • 21 May 2020 Antisense Therapeutics plans to apply for Orphan Drug Designation for ATL 1102 for Duchenne muscular dystrophy in USA and European Union
  • 21 May 2020 Antisense Therapeutics plans to make a clinical trial application to regulatory authorities for a phase II trial in Duchenne muscular dystrophy in Europe and United Kingdom
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