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HSV 1716

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Drug Profile

HSV 1716

Alternative Names: Herpes simplex virus 1716 - Virttu; HSV1716; Oncolytic HSV-1716; Seprehvir

Latest Information Update: 28 Dec 2022

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At a glance

  • Originator Crusade Laboratories
  • Developer Nationwide Children's Hospital; Pediatric Brain Tumor Consortium; Virttu Biologics
  • Class Antineoplastics; Immunotherapies; Oncolytic viruses
  • Mechanism of Action Cell death stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Glioma
  • New Molecular Entity No

Highest Development Phases

  • Phase I/II Malignant-mesothelioma
  • No development reported Glioblastoma; Glioma; Malignant melanoma; Squamous cell cancer
  • Discontinued Prostate cancer; Solid tumours

Most Recent Events

  • 28 Dec 2022 Discontinued - Phase-I for Solid tumours (In adolescents, In children, Second-line therapy or greater, In adults) in USA (Intratumoural)
  • 28 Dec 2022 Discontinued - Phase-I for Solid tumours (In adolescents, In children, Second-line therapy or greater, In adults) in USA (IV)
  • 28 Dec 2022 Discontinued - Preclinical for Prostate cancer in United Kingdom (IV)

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