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Ciclosporin intravenous - Maas Biolab/Abliva

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Drug Profile

Ciclosporin intravenous - Maas Biolab/Abliva

Alternative Names: CicloMulsion; Ciclosporin-A; Cyclosporin - Maas Biolab; Cyclosporin-A; Mitogard; Neuro-STAT®; NeuroSTAT; OWL-1410

Latest Information Update: 22 Nov 2023

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At a glance

  • Originator Maas Biolab; NeuroVive Pharmaceutical
  • Developer Abliva; Defense Threat Reduction Agency; Maas Biolab; NeuroVive Pharmaceutical; Skane University Hospital; Walter Reed Army Institute of Research
  • Class Anti-inflammatories; Antineoplastics; Antipsoriatics; Antirheumatics; Ciclosporins; Eye disorder therapies; Heart failure therapies; Neuroprotectants
  • Mechanism of Action Calcineurin inhibitors; Cyclophilin inhibitors; Free radical inhibitors; Immunosuppressants; Mitochondrial permeability transition pore inhibitors; P-glycoprotein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Amyotrophic lateral sclerosis; Traumatic brain injuries
  • New Molecular Entity No
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Traumatic brain injuries
  • Discontinued Acute kidney injury; Amyotrophic lateral sclerosis; Poisoning; Reperfusion injury

Most Recent Events

  • 17 Nov 2023 Ciclosporin intravenous licensed to Owl Therapeutics worldwide
  • 15 Jun 2020 Abliva plans a phase II trial for Traumatic brain injuries
  • 28 May 2020 NeuroVive Pharmaceutical is now called Abliva
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