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Ixabepilone - R Pharm

Drug Profile

Ixabepilone - R Pharm

Alternative Names: Azaepothilone B; BMS-247550; Epothilone B analogue; IXEMPRA; Ixempra; NSC 710428; Patupilone analogue

Latest Information Update: 29 Nov 2023

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At a glance

  • Originator GBF
  • Developer Allarity Therapeutics; Bristol-Myers Squibb; R-Pharm; Yale University
  • Class Antineoplastics; Epothilones; Macrolides; Small molecules
  • Mechanism of Action Cell cycle inhibitors; Tubulin inhibitors; Tubulin polymerisation promoters
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Breast cancer
  • Phase II Fallopian tube cancer; Ovarian cancer; Peritoneal cancer
  • No development reported Gastric cancer; Non-small cell lung cancer; Oesophageal cancer; Pancreatic cancer
  • Discontinued Cancer; Endometrial cancer; Prostate cancer

Most Recent Events

  • 21 Nov 2023 R-Pharma in collaboration with Yale university completes a phase-II clinical trial in Ovarian cancer, Fallopian Tube Cancer and Primary Peritoneal Cancer (In the elderly, Metastatic disease, Second-line therapy or greater, In adults, Combination therapy) in USA (IV) (NCT03093155)
  • 05 Jul 2023 Efficacy data from a phase II trial in Breast cancer released by Allarity Therapeutics
  • 22 Dec 2021 Vector Pharma and R-PHARM enter into a licensing agreement to market ixabepilone for Breast cancer in Morocco, Tunisia, Algeria, Libya, Egypt, Saudi Arabia, Qatar, UAE, Bahrain, Kuwait, Oman, Lebanon, Jordan, and Iraq
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