Either you have JavaScript disabled or your browser does not support Javascript . To work properly, this page requires JavaScript to be enabled.
How to enable JavaScript in your browser?

Aflibercept - Bayer/Regeneron Pharmaceuticals/Sanofi

Next Previous
X
Search
Drug Profile

Aflibercept - Bayer/Regeneron Pharmaceuticals/Sanofi

Alternative Names: aflibercept [genetical recombination]; AVE-0005; BAY-865321; EYLEA; Eylea; EYLEA HD; EYLEA® solution for intravitreal injection; Eylia; REGN3; Vascular endothelial growth factor Trap; Vascular endothelial growth factor Trap-R1R2; VEGF Trap (R1R2); VEGF Trap-Eye; Wetlia; Zaltrap; Ziv-aflibercept

Latest Information Update: 21 Aug 2024

Price : $50 *
  • Adis is an information provider. We do not sell or distribute actual drugs.
  • Final gross price and currency may vary according to local VAT and billing address.
  • Your purchase entitles you to full access to the information contained in our drug profile at the time of purchase.
  • A link to download a PDF version of the drug profile will be included in your email receipt.

At a glance

  • Originator Regeneron Pharmaceuticals
  • Developer Bayer; Bayer HealthCare Pharmaceuticals; Bayer Yakuhin; Centre Oscar Lambret; GERCOR; Greater Houston Retina Research; Guys Hospital; Hellenic Cooperative Oncology Group; Moorfields Eye Hospital; National Cancer Institute (USA); Regeneron Pharmaceuticals; Roche; Sanofi; sanofi-aventis; Tufts Medical Center; University of Ulm
  • Class Antineoplastics; Eye disorder therapies; Immunoglobulin Fc fragments; Immunoglobulin fragments; Recombinant fusion proteins
  • Mechanism of Action Placenta growth factor inhibitors; Vascular endothelial growth factor A inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Glaucoma; Retinopathy of prematurity
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Branch retinal vein occlusion; Central retinal vein occlusion; Choroidal neovascularisation; Colorectal cancer; Diabetic macular oedema; Diabetic retinopathy; Glaucoma; Retinal oedema; Retinopathy of prematurity; Wet age-related macular degeneration
  • Phase III Polypoidal choroidal vasculopathy
  • Phase II Central serous chorioretinopathy; Graves ophthalmopathy; Retinal disorders
  • No development reported Malignant ascites; Non-Hodgkin's lymphoma; Ovarian cancer; Solid tumours
  • Discontinued Non-small cell lung cancer; Pancreatic cancer; Prostate cancer

Most Recent Events

  • 24 Jul 2024 Regeneron Pharmaceuticals initiates the phase III ELARA trial in Wet-age-related-macular-degeneration and Diabetic macular edema in USA (Intravitreal, Injection) (NCT06491914)
  • 18 Jul 2024 Regeneron Pharmaceuticals plans phase III ELARA trial in Wet-age-related-macular-degeneration and Diabetic macular edema in July 2024 (intravitreal, Injection) (NCT06491914)
  • 30 Jun 2024 Regeneron Pharmaceuticals files sBLA for diabetic macular edema (DME) to US FDA

You need to be a logged in or subscribed to view this content Request demo

If your organization or you do not have a subscription, try one of the following:
  • Contacting your organization’s admin about adding this content to your AdisInsight subscription
  • Buying a PDF version of any individual profile
  • Request a free trial
If your organization has a subscription, there are several access options, even while working remotely:
  • Working within your organization’s network
  • with username/password or try to via your institution
  • Persisted access using your organization’s identifier stored in your user browser for 90 days
Back to top