Bertilimumab - Immune Pharmaceuticals

Drug Profile

Bertilimumab - Immune Pharmaceuticals

Alternative Names: Anti-eotaxin human monoclonal antibody; CAT-213; iCo-008

Latest Information Update: 22 Aug 2018

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At a glance

  • Originator Cambridge Antibody Technology
  • Developer Cambridge Antibody Technology; iCo Therapeutics; Immune Pharmaceuticals Inc
  • Class Antiallergics; Eye disorder therapies; Monoclonal antibodies
  • Mechanism of Action Chemokine CCL11 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Bullous pemphigoid
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Bullous pemphigoid; Crohn's disease; Ulcerative colitis
  • Phase I Atopic dermatitis; Non-alcoholic steatohepatitis
  • Preclinical Wet age-related macular degeneration
  • No development reported Allergic conjunctivitis; Asthma
  • Discontinued Allergic rhinitis; Ovarian cancer

Most Recent Events

  • 20 Aug 2018 Bertilimumab - Immune Pharmaceuticals receives Orphan Drug status for Bullous pemphigoid in USA
  • 30 Jul 2018 Committee for Orphan Medicinal Products (COMP) issues positive opinion for orphan drug designation for bertilimumab for Bullous pemphigoid in European Union
  • 23 May 2018 Immune Pharmaceuticals announces intention to conduct meetings with the US FDA and the EMA to discuss the planned pivotal phase II/III study for Bullous Pemphigoid later in 2018
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