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Semzuvolimab - United Biopharma

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Drug Profile

Semzuvolimab - United Biopharma

Alternative Names: dB4; dB4C7 mAb; dB4C7C22-6 mAb; mAb B4; UB-421

Latest Information Update: 28 Jan 2026

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At a glance

  • Originator United Biomedical
  • Developer Kaohsiung Medical University Chung-Ho Memorial Hospital; Kaohsiung Veterans General Hospital; United Biomedical; United BioPharma
  • Class Antiretrovirals; Monoclonal antibodies
  • Mechanism of Action HIV fusion inhibitors; Immunomodulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III HIV-1 infections

Most Recent Events

  • 28 Jan 2026 No recent reports of development identified for phase-I development in HIV-1-infections(Treatment-naive) in Taiwan (SC, Injection)
  • 04 Jan 2024 Semzuvolimab is still in phase III trials for HIV-1 infections in Taiwan, China, Thailand
  • 25 Apr 2023 United Biopharma withdraws a phase III trial prior to enrolment due to project adjustment for HIV-1 infections (Monotherapy) in China (IV) (NCT03149211)

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