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UB 421

Drug Profile

UB 421

Alternative Names: dB4; dB4C7 mAb; mAb B4; UB421

Latest Information Update: 01 Jun 2020

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At a glance

  • Originator United Biomedical
  • Developer United Biomedical; United BioPharma
  • Class Antiretrovirals; Monoclonal antibodies
  • Mechanism of Action HIV fusion inhibitors; Immunomodulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II HIV-1 infections

Most Recent Events

  • 01 Jun 2020 United BioPharma plans a phase III trial for HIV-1 infections (NCT04406727)
  • 29 May 2020 United BioPharma plans a phase II trial for HIV-I infection (Adjunctive treatment, Combination therapy) in China (IV) (NCT04404049)
  • 21 Feb 2020 United BioPharma withdraws a phase II trial for HIV-1 infections (Adjunctive treatment, Combination therapy) prior to enrolment as the study will not be submitted to authority for IND application (IV) (NCT04041362)
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