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Forodesine - Mundipharma International

Drug Profile

Forodesine - Mundipharma International

Alternative Names: BCX-1777; Fodosine; Forodesine hydrochloride; Immucillin-H; Mundesine

Latest Information Update: 14 Apr 2021

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At a glance

  • Originator Albert Einstein College of Medicine; Industrial Research Limited
  • Developer BioCryst Pharmaceuticals; Mundipharma International
  • Class Antineoplastics; Antipsoriatics; Purine nucleosides; Pyrimidinones; Small molecules
  • Mechanism of Action Immunosuppressants; Purine nucleoside phosphorylase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Adult T-cell leukaemia-lymphoma; Chronic lymphocytic leukaemia; Cutaneous T-cell lymphoma; Peripheral T-cell lymphoma; Precursor cell lymphoblastic leukaemia-lymphoma; Leukaemia; T-cell prolymphocytic leukaemia; Hairy cell leukaemia
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Peripheral T-cell lymphoma
  • No development reported Chronic lymphocytic leukaemia
  • Discontinued Cutaneous T-cell lymphoma; Haematological malignancies

Most Recent Events

  • 14 Apr 2021 Discontinued - Phase-I for Haematological malignancies (Recurrent, Second-line therapy or greater) in Japan (PO) (Mundipharma pipeline, April 2021)
  • 14 Apr 2021 Discontinued - Phase-II for Chronic lymphocytic leukaemia (Second-line therapy or greater) in USA (PO) (Mundipharma pipeline, April 2021)
  • 14 Apr 2021 Discontinued - Phase-II for Cutaneous T-cell lymphoma (Second-line therapy or greater) in USA, Australia, Switzerland, Austria, Finland, Italy, France, Germany, Spain and United Kingdom (PO) (Mundipharma pipeline, April 2021)
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