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Ezetimibe/simvastatin - Merck & Co

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Drug Profile

Ezetimibe/simvastatin - Merck & Co

Alternative Names: Inegy; MK-0653A; Simvastatin/ezetimibe; Vytorin; Zetia™/Zocor®; Zintrepid; Zocor®/Zetia™

Latest Information Update: 28 Nov 2024

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At a glance

  • Originator Merck/Schering-Plough Pharmaceuticals
  • Class Antihyperlipidaemics; Azetidines; Fluorobenzenes; Naphthalenes; Propanols; Small molecules
  • Mechanism of Action Cholesterol absorption inhibitors; HMG-CoA reductase inhibitors; NPC1L1 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Marketed Acute coronary syndromes; Hypercholesterolaemia; Hyperlipidaemia
  • Discontinued Aortic valve stenosis

Most Recent Events

  • 28 Nov 2024 Ezetimibe/simvastatin is still in phase III trials for Acute coronary syndromes in Europe (NCT00202878)
  • 18 Jan 2019 No development reported - Preregistration for Acute coronary syndromes in USA (PO)
  • 27 Apr 2017 Generic equivalent available in USA for Hypercholesterolaemia

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