Drug Profile


Alternative Names: Inegy; MK-0653A; Simvastatin/ezetimibe; Vytorin; Zetia™/Zocor®; Zintrepid; Zocor®/Zetia™

Latest Information Update: 24 Mar 2018

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At a glance

  • Originator Merck/Schering-Plough Pharmaceuticals
  • Class Antihyperlipidaemics; Azetidines; Naphthalenes; Small molecules
  • Mechanism of Action Cholesterol absorption inhibitors; HMG-CoA reductase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Marketed Acute coronary syndromes; Hypercholesterolaemia; Hyperlipidaemia
  • Discontinued Aortic valve stenosis

Most Recent Events

  • 24 Jun 2018 Biomarkers information updated
  • 27 Apr 2017 Generic equivalent available in USA for Hypercholesterolaemia
  • 28 Feb 2017 Merck has patent protection for ezetimibe/simvastatin (Vytorin®) in Europe and Japan (Merck Annual report 2016)
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