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Folitixorin - ADVENTRX

Drug Profile

Folitixorin - ADVENTRX

Alternative Names: 5-10 Methylenetetrahydrofolate; 5-FU biomodulator - ADVENTRX; ANX-510; CoFactor; Methylenetetrahydrofolic acid

Latest Information Update: 30 Oct 2008

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At a glance

  • Originator Sahlgrenska University Hospital; University of Southern California
  • Developer ADVENTRX Pharmaceuticals
  • Class 3-ring heterocyclic compounds; Antineoplastics; Chemoprotectants; Chemosensitisers; Folic acids; Imidazolidines; Pyrimidinones; Small molecules; Tetrahydrofolates
  • Mechanism of Action Antimetabolites; Thymidylate synthase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Pancreatic cancer
  • New Molecular Entity No

Highest Development Phases

  • Discontinued Breast cancer; Colorectal cancer; Pancreatic cancer

Most Recent Events

  • 23 Oct 2008 Discontinued - Phase-II for Breast cancer in Argentina (IV)
  • 23 Oct 2008 Discontinued - Phase-II for Breast cancer in Mexico (IV)
  • 23 Oct 2008 Discontinued - Phase-II for Breast cancer in Peru (IV)
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