Drug Profile


Alternative Names: CBD4124; CDB-4124; Proellex; Proellex®-V; Progenta; Telapristone acetate

Latest Information Update: 04 Nov 2017

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At a glance

  • Originator National Institute of Child Health and Human Development
  • Developer Northwestern University Feinberg School of Medicine; Repros Therapeutics
  • Class Antineoplastics; Antiprogestogens; Norpregnadienes; Small molecules
  • Mechanism of Action Selective progesterone receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Breast cancer; Endometriosis; Uterine leiomyoma
  • Suspended Anaemia

Most Recent Events

  • 24 Jun 2018 Biomarkers information updated
  • 04 Nov 2017 No recent reports of development identified for preclinical development in Endometriosis in USA (Vaginal, Suppository)
  • 17 Jul 2017 Repros Therapeutics completes a phase II trial in Endometriosis in USA and Argentina (NCT01728454)
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