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Botulinum toxin A - Merz Pharma

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Drug Profile

Botulinum toxin A - Merz Pharma

Alternative Names: Bocouture; Incobotulinum toxin A; NT 201L; NT-201; Xeomeen; XEOMIN; Xeomin; Xeomin cosmetic; Zeomaine

Latest Information Update: 09 Oct 2024

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At a glance

  • Originator BIOTECON Therapeutics
  • Developer Merz Aesthetics; Merz Pharma; Merz Pharmaceuticals GmbH; Yale University
  • Class Analgesics; Anti-inflammatories; Antiarrhythmics; Antidepressants; Antimigraines; Antipruritics; Antispasmodics; Bacterial proteins; Bacterial toxins; Botulinum toxins; Eye disorder therapies; Foot disorder therapies; Muscle relaxants; Recombinant proteins; Skin disorder therapies; Urologics; Vascular disorder therapies
  • Mechanism of Action Acetylcholine inhibitors; Glutamate antagonists; Membrane transport protein modulators; Neuromuscular blocking agents
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Marketed Blepharospasm; Dystonia; Glabellar lines; Muscle spasticity; Sialorrhoea; Torticollis
  • Phase III Atrial fibrillation; Facial wrinkles
  • Phase II Alopecia; Essential tremor; Neuropathic pain; Skin aging; Trigeminal neuralgia
  • Phase I Unspecified
  • No development reported Pain
  • Discontinued Cancer pain

Most Recent Events

  • 09 Oct 2024 Phase-II clinical trials in Neuropathic pain in France, Hungary, Spain (SC) (NCT06091020)
  • 05 Aug 2024 Pharmacodynamics data from preclinical trial in Neuropathic pain presented at the World Congress of Psychiatry (WCP 2024)
  • 14 Jun 2024 Swissmedic approves incobotulinumtoxinA for treatment of lower limb Muscle spasticity in Switzerland

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