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Riociguat - Bayer

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Drug Profile

Riociguat - Bayer

Alternative Names: Adempas; BAY-32521; BAY-63-2521

Latest Information Update: 05 Nov 2023

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At a glance

  • Originator Bayer
  • Class 2 ring heterocyclic compounds; Antifibrotics; Carbamates; Diamines; Fluorobenzenes; Pyrazoles; Pyridines; Pyrimidines; Skin disorder therapies; Small molecules; Vascular disorder therapies
  • Mechanism of Action Guanylate cyclase stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Systemic scleroderma; Pulmonary hypertension; Pulmonary arterial hypertension
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Pulmonary arterial hypertension; Pulmonary hypertension
  • Phase II Cystic fibrosis; Systemic scleroderma
  • No development reported Raynaud's disease

Most Recent Events

  • 22 Feb 2023 No development reported - Phase-III for Pulmonary hypertension in Sweden, Greece, Ireland, Netherlands, United Kingdom, Spain, Slovakia, Portugal, Poland, Italy, Germany, Denmark, Czech Republic, Belgium, Austria, Thailand (PO) (Bayer pipeline, February 2023)
  • 17 Feb 2021 No development reported - Phase-II for Raynaud's disease in Germany (PO) (Bayer website, February 2020)
  • 08 Sep 2020 Efficacy and safety data from the phase III PATENT-1 trial in Pulmonary arterial hypertension release by Bayer

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