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Mavrilimumab - CSL/Kiniksa Pharmaceuticals

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Drug Profile

Mavrilimumab - CSL/Kiniksa Pharmaceuticals

Alternative Names: Anti-GM-CSFR monoclonal antibody - MedImmune; CAM-3001; KPL-301

Latest Information Update: 05 Nov 2023

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At a glance

  • Originator Zenyth Therapeutics
  • Developer Kiniksa Pharmaceuticals; MedImmune
  • Class Anti-infectives; Anti-inflammatories; Antirheumatics; Cardiovascular therapies; Monoclonal antibodies; Vascular disorder therapies
  • Mechanism of Action Granulocyte macrophage colony stimulating factor antagonists; Granulocyte-macrophage colony stimulating factor receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Giant cell arteritis
  • New Molecular Entity Yes
  • Available For Licensing Yes - Cardiovascular disorders

Highest Development Phases

  • Phase II Giant cell arteritis
  • Phase I Cardiovascular disorders
  • Discontinued Inflammation; Rheumatoid arthritis; SARS-CoV-2 acute respiratory disease

Most Recent Events

  • 01 Nov 2022 Mavrilimumab - CSL/Kiniksa Pharmaceuticals is available for licensing as of 01 Nov 2022. www.kiniksa.com 9372285
  • 19 Aug 2022 Phase-I clinical trials in Cardiovascular disorders in USA (unspecified route), as of August 2022 (Kiniksa Pharmaceuticals pipeline, August 2022)
  • 01 Jun 2022 Pharmacodynamics data from preclinical studies in Giant cell arteritis at the 23rd Annual Congress of the European League Against Rheumatism (EULAR-2022)

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