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Mavrilimumab - Kiniksa Pharmaceuticals

Drug Profile

Mavrilimumab - Kiniksa Pharmaceuticals

Alternative Names: Anti-GM-CSFR monoclonal antibody - MedImmune; CAM-3001; KPL-301

Latest Information Update: 05 Nov 2019

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At a glance

  • Originator Zenyth Therapeutics
  • Developer Kiniksa Pharmaceuticals; MedImmune
  • Class Antirheumatics; Monoclonal antibodies; Vascular disorder therapies
  • Mechanism of Action Granulocyte-macrophage colony stimulating factor receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Giant cell arteritis
  • Discontinued Rheumatoid arthritis

Most Recent Events

  • 12 Jun 2019 Pharmacodynamics data from a preclinical trial in Giant cell arteritis presented at the 20th Annual Congress of the European League Against Rheumatism (EULAR-2019)
  • 14 Mar 2019 Phase-II clinical trials in Giant cell arteritis (In the elderly, In adults) in Belgium, Italy, Netherlands, Serbia, Slovenia, United Kingdom, Germany, Croatia and USA (SC) (NCT03827018) (EudraCT2018-001003-36)
  • 21 Dec 2018 Phase-II clinical trials in Giant cell arteritis (In the elderly, In adults) in New Zealand, Australia, Spain (SC) (NCT03827018)
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