Drug Profile

TM-601-I-131

Alternative Names: 131-I-labelled chlorotoxin; 131-I-labelled TM-601; ¹³¹I-TM-601

Latest Information Update: 23 Jan 2020

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At a glance

Originator TransMolecular
Class Antineoplastics; Iodine radioisotopes; Venoms
Mechanism of Action Angiogenesis inhibitors; Apoptosis stimulants; Ionising radiation emitters

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

Yes - Glioma; Malignant melanoma
New Molecular Entity Yes

Highest Development Phases

Discontinued Glioma; Malignant melanoma; Solid tumours

Most Recent Events

08 Dec 2015 Discontinued - Phase-I for Solid tumours (Metastatic disease) in USA (IV)
08 Dec 2015 Discontinued - Phase-I/II for Glioma in USA (IV)
08 Dec 2015 Discontinued - Phase-I/II for Malignant melanoma (Metastatic disease) in USA (IV)

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