Drug Profile


Alternative Names: 131-I-labelled chlorotoxin; 131-I-labelled TM-601; 131I-TM-601

Latest Information Update: 07 Jan 2016

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At a glance

  • Originator TransMolecular
  • Class Antineoplastics; Iodine radioisotopes; Venoms
  • Mechanism of Action Angiogenesis inhibitors; Apoptosis stimulants; Ionising radiation emitters
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Glioma; Malignant melanoma
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Glioma; Malignant melanoma; Solid tumours

Most Recent Events

  • 08 Dec 2015 Discontinued - Phase-I for Solid tumours (Metastatic disease) in USA (IV)
  • 08 Dec 2015 Discontinued - Phase-I/II for Glioma in USA (IV)
  • 08 Dec 2015 Discontinued - Phase-I/II for Malignant melanoma (Metastatic disease) in USA (IV)
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