Drug Profile

PTI 501

Alternative Names: morphine-naloxone

Latest Information Update: 19 Mar 2026

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At a glance

Originator Albert Einstein College of Medicine
Developer Pain Therapeutics
Class Enzymes; Pentosyltransferases; Recombinant proteins
Mechanism of Action Opioid mu receptor agonists; Opioid receptor antagonists

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity No

10 Mar 2026 Cassava Sciences is now called Filana Therapeutics
27 Mar 2019 Pain Therapeutics is now called Cassava Sciences
07 May 2002 Enrolment has been completed in a phase II clinical trial in patients with severe postoperative pain

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