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Drug Profile


Alternative Names: Denufosol tetrasodium; INS 37217; INS 37217 ophthalmic; INS37217 Respiratory

Latest Information Update: 18 Feb 2011

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At a glance

  • Originator Inspire Pharmaceuticals
  • Class Decongestants; Expectorants; Eye disorder therapies; Pyrimidine nucleosides; Small molecules
  • Mechanism of Action Purinoceptor P2U agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Cystic fibrosis

Highest Development Phases

  • Discontinued Cystic fibrosis; Dry eyes; Perennial allergic rhinitis; Retinal disorders; Retinal oedema; Sinusitis

Most Recent Events

  • 18 Feb 2011 Discontinued - Phase-II for Cystic fibrosis in USA (Inhalation)
  • 18 Feb 2011 Discontinued - Phase-III for Cystic fibrosis in Australia (Inhalation)
  • 18 Feb 2011 Discontinued - Phase-III for Cystic fibrosis in Canada (Inhalation)
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