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Belatacept - Bristol-Myers Squibb

Drug Profile

Belatacept - Bristol-Myers Squibb

Alternative Names: BMS-224818; CTLA4-IgLEA29Y; LEA 29Y; Nulojix

Latest Information Update: 13 Feb 2019

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At a glance

  • Originator Bristol-Myers Squibb
  • Developer Bristol-Myers Squibb; Emory University
  • Class Immunoconjugates; Immunoglobulin fusion proteins; Recombinant fusion proteins
  • Mechanism of Action CD28 antigen inhibitors; CD80 antigen inhibitors; Immunosuppressants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Renal transplant rejection
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Renal transplant rejection
  • Discontinued Liver transplant rejection; Rheumatoid arthritis

Most Recent Events

  • 13 Feb 2019 Belatacept is still in phase III trial for Renal transplant rejection (Prevention, Treatment-experienced, In adults, In the elderly) in Argentina, Colombia and Norway (NCT01820572)
  • 13 Feb 2019 No development reported - Phase-III for Renal transplant rejection (Prevention) in Brazil (IV)
  • 13 Feb 2019 No development reported - Phase-III for Renal transplant rejection (Prevention) in Chile (IV)
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