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Minocycline controlled-release - OraPharma

Drug Profile

Minocycline controlled-release - OraPharma

Alternative Names: Arestin; Arestin LCM; Minocycline microspheres

Latest Information Update: 16 Oct 2021

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At a glance

  • Originator Wyeth
  • Developer OraPharma; Wyeth
  • Class Amides; Anti-inflammatories; Antiacnes; Antibacterials; Dimethylamines; Eye disorder therapies; Neuroprotectants; Skin disorder therapies; Small molecules; Tetracyclines
  • Mechanism of Action Protein 30S ribosomal subunit inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Marketed Periodontitis
  • Discontinued Peri-implantitis

Most Recent Events

  • 09 Aug 2016 Discontinued - Phase-III for Peri-implantitis in United Kingdom, Sweden, Germany and USA (Subgingival) based on analysis of a phase III study data (Valeant Pharmaceuticals Form10-Q, August 2016)
  • 24 Jun 2014 OraPharma completes a phase III trial in Peri-implantitis in USA, United Kingdom, Germany & Sweden (NCT01539564)
  • 14 Jun 2014 Phase-III clinical trials in Peri-implantitis in United Kingdom & Sweden (Subgingival)
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