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Dextromethorphan/quinidine - Avanir Pharmaceuticals

Drug Profile

Dextromethorphan/quinidine - Avanir Pharmaceuticals

Alternative Names: AVP-923; Dextromethorphan HBr/quinidine sulfate; Dextromethorphan hydrobromide/quinidine sulfate; Neurodex; Nuedexta; Quinidine/dextromethorphan; Zenvia

Latest Information Update: 05 Nov 2023

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At a glance

  • Originator Center for Neurologic Study
  • Developer Avanir Pharmaceuticals
  • Class Analgesics; Antimigraines; Antitussives; Behavioural disorder therapies; Cinchona alkaloids; Morphinans; Quinuclidines; Small molecules
  • Mechanism of Action Cytochrome P 450 enzyme system inhibitors; NMDA receptor antagonists; Norepinephrine plasma membrane transport protein inhibitors; Serotonin plasma membrane transport protein inhibitors; Sigma-1 receptor agonists; Sodium channel antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Amyotrophic lateral sclerosis
  • New Molecular Entity No

Highest Development Phases

  • Marketed Emotional lability
  • Discontinued Agitation; Diabetic neuropathies; Drug-induced dyskinesia; Migraine; Neuropathic pain

Most Recent Events

  • 14 Feb 2019 Chemical structure information added
  • 27 Nov 2018 No development reported - Phase-II for Agitation in USA (PO)
  • 27 Nov 2018 No development reported - Phase-II for Migraine in USA (PO)
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