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Gantenerumab - Roche

Drug Profile

Gantenerumab - Roche

Alternative Names: R-1450; RG-1450; RO-4909832

Latest Information Update: 10 Jun 2020

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At a glance

  • Originator MorphoSys
  • Developer Chugai Pharmaceutical; Roche; Washington University School of Medicine
  • Class Antidementias; Monoclonal antibodies; Neuroprotectants
  • Mechanism of Action Amyloid beta-protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Alzheimer's disease

Most Recent Events

  • 22 May 2020 Phase-III clinical trials in Alzheimer's disease (Treatment-experienced, In children, In adults, In the elderly) in Canada (SC) (NCT04339413) (EudraCT2019-004431-23)
  • 05 May 2020 Roche plans a phase III trial for Alzheimer's disease in Argentina, Chile, Mexico (SC) in August 2020 (NCT04374253)
  • 25 Apr 2020 Efficacy data from the phase III open-label extension SCarlet RoAD and Marguerite RoAD trials in Alzheimer's disease presented at the 72nd Annual Meeting of the American Academy of Neurology (AAN-2020)
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