Either you have JavaScript disabled or your browser does not support Javascript . To work properly, this page requires JavaScript to be enabled.
How to enable JavaScript in your browser?

AEOL 10150

Drug Profile

AEOL 10150

Alternative Names: AEOL-10150; MnTDEIP

Latest Information Update: 10 Mar 2023

Price : $50 *
  • Adis is an information provider. We do not sell or distribute actual drugs.
  • Final gross price and currency may vary according to local VAT and billing address.
  • Your purchase entitles you to full access to the information contained in our drug profile at the time of purchase.
  • A link to download a PDF version of the drug profile will be included in your email receipt.

At a glance

  • Originator Duke University; National Jewish Medical and Research Center
  • Developer Aeolus Pharmaceuticals Inc; National Institutes of Health (USA); National Jewish Medical and Research Center; United States Army Medical Research Institute of Chemical Defense; University of Colorado at Denver
  • Class Oxidoreductases; Porphyrins; Small molecules
  • Mechanism of Action Angiogenesis inhibitors; Antioxidants; Free radical scavengers; Oxygen radical scavengers; Reactive oxygen species inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Amyotrophic lateral sclerosis; Acute radiation syndrome; Idiopathic pulmonary fibrosis
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Acute lung injury; Acute radiation syndrome; Amyotrophic lateral sclerosis; Chronic obstructive pulmonary disease; Cystic fibrosis; Diabetes mellitus; Gastrointestinal disorders; Idiopathic pulmonary fibrosis; Lung disorders; Mucositis; Poisoning; Radiation injuries; Skin disorders; Solid tumours; Spinal cord injuries; Stroke

Most Recent Events

  • 10 Mar 2023 Discontinued - Phase-I for Amyotrophic lateral sclerosis in USA (SC), before March 2023 (NDR batch 29)
  • 10 Feb 2023 Discontinued - Phase-I for Acute radiation syndrome (In volunteers) in USA (SC)
  • 10 Feb 2023 Discontinued - Preclinical for Acute lung injury in USA (SC)
Subscriber content

You need to be a logged in subscriber to view this content.

If your organization has a subscription then there are several options available to help you access AdisInsight, even while working remotely.

  • IP authentication when working within your organization’s network.
  • with username/password or try via your institution
  • Persisted access using your organization’s identifier stored in your user browser for 90 days.
  • Contact us at AsktheExpert.AdisInsight@springer.com for assistance.

If your organization does not have a subscription to this content. To gain full access to the content and functionality of the AdisInsight database try one of the following.

  • Contact your organization’s admin about adding this content to your AdisInsight subscription
  • Buy a PDF version of the profile.
  • Request a free trial
Back to top