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Research programme: 5T4 monoclonal antibody conjugates - Oxford BioMedica/Pfizer

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Drug Profile

Research programme: 5T4 monoclonal antibody conjugates - Oxford BioMedica/Pfizer

Alternative Names: 5T4 MAb-toxin; Anti-5T4 antibody; CME-548; OBA1-H8

Latest Information Update: 04 Nov 2017

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At a glance

  • Originator Oxford BioMedica
  • Developer Pfizer
  • Class Aminoglycosides; Antineoplastics; Drug conjugates; Enediynes; Immunotoxins; Monoclonal antibodies
  • Mechanism of Action Apoptosis stimulants; Immunomodulators; Membrane glycoprotein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • No development reported Cancer

Most Recent Events

  • 04 Nov 2017 No recent reports of development identified for preclinical development in Cancer in USA (IV)
  • 06 Sep 2013 Preclinical development in Cancer is ongoing in USA
  • 04 May 2011 Oxford BioMedica broadens 5T4 antibody collaboration with Pfizer; Pfizer granted non-exclusive rights for the diagnostic use of 5T4 antibodies in an amendment to an existing licensing agreement

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