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Yttrium 90-labelled edotreotide

Drug Profile

Yttrium 90-labelled edotreotide

Alternative Names: 90Y-SDZ-SMT-487; 90Y-DOTA-D-Phe1-Tyr3-octreotide; 90Y-SMT 487; OctreoTher™; Onalta; SMT-487; Y-90 SMT-487; Y-90-DOTA-tyr3-Octreotide; Yttrium 90 labelled endotreotide; Yttrium 90 labelled SMT 487

Latest Information Update: 11 Dec 2015

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At a glance

  • Originator Novartis
  • Developer Molecular Insight Pharmaceuticals; University of Iowa
  • Class Antineoplastics; Cyclic peptides; Organotechnetium compounds; Radiopharmaceuticals
  • Mechanism of Action Ionising radiation emitters
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Neuroendocrine tumours
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Neuroendocrine tumours

Most Recent Events

  • 22 Jan 2013 Molecular Insight Pharmaceuticals has been acquired by Progenics Pharmaceuticals
  • 06 Aug 2010 Yttrium 90-labelled edotreotide is still in phase II trials for Neuroendocrine tumours in USA
  • 04 Sep 2009 Yttrium 90-labelled edotreotide sub-licensed to BioMedica Life Sciences in specific countries in Europe, the Middle East, North Africa, Russia, and Turkey
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