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Liprotamase - Alkira Therapeutics

Drug Profile

Liprotamase - Alkira Therapeutics

Alternative Names: ALTU-135; Liprotamase; LY-3031642; Sollpura; TheraCLEC™-Total; Trizytek™

Latest Information Update: 31 Dec 2018

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At a glance

  • Originator Cystic Fibrosis Foundation Therapeutics
  • Developer Anthera Pharmaceuticals; Cystic Fibrosis Foundation Therapeutics
  • Class Amylases; Carboxylic ester hydrolases; Pancreatic enzymes; Peptide hydrolases
  • Mechanism of Action Amylase replacements; Lipase replacements; Peptide hydrolase replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Exocrine pancreatic insufficiency
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Exocrine pancreatic insufficiency

Most Recent Events

  • 28 Mar 2018 Anthera Pharmaceuticals has 4 European patents and 16 non-European issued patents for liprotamase
  • 12 Mar 2018 Discontinued - Phase-III for Exocrine pancreatic insufficiency (In adolescents, In children, In infants, In adults) in USA (PO) (NCT02823964)
  • 12 Mar 2018 Discontinued - Phase-III for Exocrine pancreatic insufficiency (In adolescents, In children, In the elderly, In adults) in USA, United Kingdom, Spain, Poland, Lithuania, Israel, Hungary (PO) (NCT03051490)
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