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Tonapofylline

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Drug Profile

Tonapofylline

Alternative Names: Adentri; BG-9928

Latest Information Update: 16 Mar 2010

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At a glance

  • Originator CV Therapeutics
  • Developer Biogen Idec
  • Class Heart failure therapies; Small molecules; Xanthines
  • Mechanism of Action Adenosine A1 receptor antagonists; Adenosine A2B receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No

Highest Development Phases

  • Discontinued Acute heart failure; Chronic heart failure

Most Recent Events

  • 17 Apr 2009 CV Therapeutics has been acquired and merged into Gilead Sciences
  • 22 Aug 2008 Phase-III clinical trials in Acute heart failure in World (IV)
  • 16 Aug 2007 Final results from a phase II clinical trial in Chronic heart failure added to the Heart Failure therapeutic trials section

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