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Modified vaccinia Ankara - Bavarian Nordic

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Drug Profile

Modified vaccinia Ankara - Bavarian Nordic

Alternative Names: IMVAMUNE; IMVAMUNE® liquid-frozen; IMVAMUNE® freeze-dried; IMVANEX; JYNNEOS; Monkeypox vaccine - Bavarian Nordic; MVA-BN; MVA-BN® Smallpox; MVA-BN® freeze-dried; MVA-BN® liquid-frozen; MVA-BN® smallpox vaccine; Smallpox and monkeypox vaccine - Bavarian Nordic

Latest Information Update: 10 Oct 2025

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At a glance

  • Originator Bavarian Nordic
  • Developer Bavarian Nordic; Centers for Disease Control and Prevention; Coalition for Epidemic Preparedness Innovations; National Institute of Allergy and Infectious Diseases; National Institutes of Health (USA)
  • Class Viral vaccines
  • Mechanism of Action Immunostimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Marketed Monkeypox; Smallpox; Vaccinia virus infections
  • Phase II Orthopoxvirus infections

Most Recent Events

  • 07 Oct 2025 Bavarian Nordic announces intention to submit MAA to EMA for Orthopox virus, Smallpox and Monkey pox (In Children, In adolescent, Prevention) in 2026
  • 30 Sep 2025 Bavarian Nordic plans a phase II trial for Monkeypox in October 2025 (SC) (NCT07199569)
  • 29 May 2025 Phase-III clinical trials in Monkeypox (In infants, Prevention) in Democratic Republic of the Congo (SC) (NCT06844487)

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