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Vorapaxar - Merck & Co/Old API Wind-down

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Drug Profile

Vorapaxar - Merck & Co/Old API Wind-down

Alternative Names: MK-5348; SCH-530348; TRA; TRA-SCH-530348; Vorapaxar sulfate; Zontivity

Latest Information Update: 05 Nov 2023

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At a glance

  • Originator Schering-Plough
  • Developer Duke Clinical Research Institute; Kirby Institute for infection and immunity in society; Merck & Co; Old API Wind-down Ltd
  • Class 3-ring heterocyclic compounds; Antithrombotics; Carbamates; Cardiovascular therapies; Lactones; Pyridines
  • Mechanism of Action PAR 1 receptor antagonists; Thrombin receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Arterial thrombosis
  • Phase I/II Blood coagulation disorders; Inflammation
  • No development reported Cerebral infarction

Most Recent Events

  • 01 Apr 2021 No development reported - Phase-I/II for Blood coagulation disorders in Australia (PO)
  • 01 Apr 2021 No development reported - Phase-I/II for Inflammation in Australia (PO)
  • 06 Feb 2019 Aralez Pharmaceuticals is now called Old API Wind-down

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