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Drug Profile


Alternative Names: Blastokinin; CC10; CC16; CCSP; CG 100; CG 367; CG201; CG459; Clara cell 10 kDa protein; Claragen; PCB-binding protein; Recombinant human CC10 protein; Recombinant human Clara cell 10 kDa protein; Recombinant human secretoglobin 1A1; rhCC10; SCGB1A1; Urine protein-1

Latest Information Update: 10 Mar 2023

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At a glance

  • Originator Unknown
  • Developer Brigham and Womens Hospital; Therabron Therapeutics; Tufts-New England Medical Center
  • Class Anti-inflammatories; Recombinant proteins; Respiratory stimulants
  • Mechanism of Action Protein replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Bronchopulmonary dysplasia; Bronchiolitis obliterans
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Bronchopulmonary dysplasia
  • Phase I/II Sinusitis
  • No development reported Bronchiolitis obliterans
  • Discontinued Acute lung injury; Asthma; Burns; Chronic obstructive pulmonary disease; Influenza virus infections; Pneumonia; Respiratory distress syndrome

Most Recent Events

  • 10 Mar 2023 Discontinued - Preclinical for Acute lung injury in USA (Parenteral)
  • 10 Mar 2023 Discontinued - Preclinical for Asthma in USA (Inhalation)
  • 10 Mar 2023 Discontinued - Preclinical for Burns in USA (Parenteral)
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