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Vapendavir - Altesa Biosceinces/Vaxart

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Drug Profile

Vapendavir - Altesa Biosceinces/Vaxart

Alternative Names: BTA-798

Latest Information Update: 24 Feb 2026

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At a glance

  • Originator Biota Holdings
  • Developer Altesa Biosciences; Aviragen Therapeutics; Vaxart
  • Class Antivirals; Benzoxazoles; Ethers; Piperidines; Pyridazines; Small molecules
  • Mechanism of Action Capsid protein inhibitors; Rhinovirus replication inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Rhinovirus infections

Most Recent Events

  • 19 Feb 2026 Altesa BioSciences plans a phase IIb CARDINAL trial for Chronic obstructive pulmonary disease and Rhinovirus infections in the US and UK in Q2 2026
  • 28 Sep 2025 Vapendavir is still in phase-II trials for Rhinovirus infections (In volunteers) in United Kingdom (PO, capsule)
  • 28 Sep 2025 Adverse events data from a phase-IIa trial in Rhinovirus infections (In volunteers) released by Altesa Biosceinces

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