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KOS 862

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Drug Profile

KOS 862

Alternative Names: Epothilone D; KOS-862; R 1492; Recombinant epothilone D

Latest Information Update: 24 Oct 2021

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At a glance

  • Originator Memorial Sloan-Kettering Cancer Center
  • Class Antineoplastics; Epothilones; Small molecules
  • Mechanism of Action Tubulin inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No

Highest Development Phases

  • Discontinued Breast cancer; Colorectal cancer; Non-small cell lung cancer; Prostate cancer; Solid tumours

Most Recent Events

  • 27 Feb 2007 Discontinued - Phase-I for Solid tumours in USA (IV-infusion)
  • 27 Feb 2007 Discontinued - Phase-II for Breast cancer in USA (IV-infusion)
  • 05 Jun 2006 Data presented at the 42nd Annual Meeting of the American Society of Clinical Oncology (ASCO-2006) have been added to the adverse events and therapeutic trials sections

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