Piclidenoson - Can-Fite Biopharma

Drug Profile

Piclidenoson - Can-Fite Biopharma

Alternative Names: CF-101; IB-MECA; SI-615

Latest Information Update: 29 Mar 2018

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At a glance

  • Originator Can-Fite BioPharma
  • Class Amides; Anti-inflammatories; Antineoplastics; Antirheumatics; Iodobenzenes; Neuroprotectants; Purine nucleosides; Ribonucleosides; Small molecules
  • Mechanism of Action Adenosine A3 receptor agonists; Apoptosis inhibitors; Immunosuppressants; Interleukin 17 receptor antagonists; Interleukin-23 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase III Rheumatoid arthritis
  • Phase II/III Plaque psoriasis
  • Phase II Glaucoma
  • Phase I Uveitis
  • Preclinical Osteoarthritis
  • Discontinued Colorectal cancer; Dry eyes; Solid tumours

Most Recent Events

  • 30 Jan 2018 Can-Fite BioPharma withdraws a phase II trial prior to enrolment for Osteoarthritis in Israel as the company has decided not to conduct the study (PO) (NCT00837291)
  • 30 Jan 2018 Can-Fite BioPharma withdraws a phase II trial prior to enrolment as the company decided not to conduct the study for Uveitis in Israel (PO) (NCT01905124)
  • 08 Jan 2018 Can-Fite Biopharma and Gebro Pharma enters into an exclusive distribution agreement for piclidenoson for Psoriasis and Rheumatoid arthritis in Austria, Spain and Switzerland
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