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EN 101

Drug Profile

EN 101

Alternative Names: EN-101; Monarsen

Latest Information Update: 23 Apr 2011

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At a glance

  • Originator Hebrew University of Jerusalem
  • Developer Amarin Corporation
  • Class Oligodeoxyribonucleotides
  • Mechanism of Action Acetylcholinesterase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Myasthenia gravis
  • Available For Licensing Yes - Amyotrophic lateral sclerosis; Inflammatory bowel diseases; Myasthenia gravis

Highest Development Phases

  • Discontinued Amyotrophic lateral sclerosis; Inflammatory bowel diseases; Myasthenia gravis

Most Recent Events

  • 08 Nov 2010 EN 101 is available for worldwide licensing in myasthenia gravis, inflammatory bowel disease and amyotrophic lateral sclerosis as of 06 Oct 2008. http://www.amarincorp.com
  • 18 Jun 2009 Suspended - Preclinical for Amyotrophic lateral sclerosis (PO)
  • 18 Jun 2009 Suspended - Preclinical for Inflammatory bowel disease (PO)
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