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Beperminogene perplasmid - AnGes

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Drug Profile

Beperminogene perplasmid - AnGes

Alternative Names: AMG 0001 01; AMG-0001; Collategene; Hepatocyte growth factor gene therapy - AnGes; HGF Plasmid-AnGes

Latest Information Update: 06 Dec 2025

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At a glance

  • Originator AnGes MG
  • Developer AnGes; Er-Kim Ilac; Kamada
  • Class Antiparkinsonians; Gene therapies; Ischaemic heart disorder therapies; Vascular disorder therapies
  • Mechanism of Action Angiogenesis inducing agents; Gene transference; Hepatocyte growth factor expression stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No
  • Available For Licensing Yes - Ischaemic heart disorders; Lymphoedema; Parkinson's disease

Highest Development Phases

  • Preregistration Chronic limb-threatening ischemia
  • Phase II Arteriosclerosis obliterans
  • Phase I/II Lymphoedema
  • No development reported Ischaemic heart disorders; Parkinson's disease

Most Recent Events

  • 01 Dec 2025 Mitsubishi Tanabe Pharma Corporation is now called Tanabe Pharma Corporation
  • 05 Nov 2025 Updated efficacy data from the phase II LEGEND 1 trial in Arteriosclerosis obliterans released by AnGes
  • 08 Aug 2025 AnGes decides to proceed with preparations for BLA for Beperminogene perplasmid following favorable phase II results and ongoing consultations with the FDA

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