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Beperminogene perplasmid - AnGes

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Drug Profile

Beperminogene perplasmid - AnGes

Alternative Names: AMG 0001 01; AMG-0001; Collategene; Hepatocyte growth factor gene therapy - AnGes; HGF Plasmid-AnGes

Latest Information Update: 28 Jan 2025

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At a glance

  • Originator AnGes MG
  • Developer AnGes; Er-Kim Ilac; Kamada
  • Class Antiparkinsonians; Gene therapies; Ischaemic heart disorder therapies; Vascular disorder therapies
  • Mechanism of Action Angiogenesis inducing agents; Gene transference; Hepatocyte growth factor expression stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No
  • Available For Licensing Yes - Ischaemic heart disorders; Lymphoedema; Parkinson's disease

Highest Development Phases

  • Preregistration Chronic limb-threatening ischemia
  • Phase II Arteriosclerosis obliterans
  • Phase I/II Lymphoedema
  • No development reported Ischaemic heart disorders; Parkinson's disease

Most Recent Events

  • 16 Nov 2024 Efficacy and adverse event data from the phase II LEGEND 1 trial in Arteriosclerosis obliterans presented at the American Heart Association Scientific Sessions 2024 (AHA-2024)
  • 18 Sep 2024 Beperminogene perplasmid - AnGes receives Breakthrough Therapy status for Peripheral arterial disorders in USA
  • 26 Aug 2024 Mitsubishi Tanabe Pharma Corporation terminates its licence for Beperminogene perplasmid in Japan and USA

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