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Drug Profile


Alternative Names: Antigen-presenting autologous dendritic cells - Lineage Cell Therapeutics; AST-VAC1; Cancer vaccine - Argos/Geron; GRNVAC 1; hTERT RNA vaccine - Argos/Geron; RNA-loaded autologous dendritic cell vaccine - Argos/Geron; VAC1

Latest Information Update: 27 Dec 2019

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At a glance

  • Originator Argos Therapeutics Inc; Geron Corporation
  • Developer Asterias Biotherapeutics; Lineage Cell Therapeutics
  • Class Cancer vaccines; Dendritic cell vaccines
  • Mechanism of Action Immunostimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Acute myeloid leukaemia
  • Discontinued Malignant melanoma; Prostate cancer

Most Recent Events

  • 31 Jul 2019 BioTime is now called Lineage Cell Therapeutics
  • 11 Mar 2019 Asterias Biotherapeutics has been acquired and merged into BioTime
  • 28 Mar 2017 Asterias Biotherapeutics has patent protection for VAC 1 in South Korea, Israel, Singapore and other jurisdictions (Asterias Biotherapeutics form 10-k, March 2017)
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