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Lucanthone - Assertio Therapeutics

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Drug Profile

Lucanthone - Assertio Therapeutics

Alternative Names: Lucanthone hydrochloride; Tixantone

Latest Information Update: 12 Jan 2024

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At a glance

  • Originator Albert Einstein College of Medicine
  • Developer Assertio Therapeutics; University of Alabama at Birmingham
  • Class Antineoplastics; Antiparasitics; Radiosensitisers; Small molecules; Thioxanthenes; Xanthones
  • Mechanism of Action DNA-apurinic apyrimidinic site lyase inhibitors; Type II DNA topoisomerase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Brain metastases; Breast cancer; Glioblastoma

Most Recent Events

  • 30 Jan 2018 Spectrum Pharmaceuticals withdraws a phase II trial in Brain metastases (Adjunctive treatment) in USA due to pending resolution of study drug issues (PO) (NCT02014545)
  • 10 Aug 2015 The University of Alabama at Birmingham and Spectrum Pharmaceuticals suspend a phase II trial in Brain metastases (Adjunctive treatment) in USA, as the principal investigator left the university (PO) (NCT02014545)
  • 30 Nov 2013 Phase-II clinical trials in Brain metastases in USA (PO)

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