Tasquinimod - Active Biotech
Alternative Names: ABR-215050; TASQLatest Information Update: 27 Aug 2026
At a glance
- Originator Active Biotech
- Developer Active Biotech; Ipsen; University of Pennsylvania
- Class Amides; Antineoplastics; Fluorinated hydrocarbons; Quinolines; Small molecules
- Mechanism of Action Angiogenesis inhibitors; Calgranulin B modulators; Immunomodulators; Thrombospondin 1 agonists
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Orphan Drug Status
Yes - Multiple myeloma; Myelofibrosis
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
- Available For Licensing Yes - Multiple myeloma
Highest Development Phases
- Phase II Myelofibrosis
- Phase I/II Multiple myeloma
- Preclinical Acute myeloid leukaemia; Myelodysplastic syndromes
- Discontinued Gastric cancer; Liver cancer; Ovarian cancer; Prostate cancer; Renal cancer
Most Recent Events
- 18 Aug 2026 Active Biotech, Icahn School of Medicine and Myeloproliferative Neoplasms Research Consortium agree to co-develop tasquinimod for Myelofibrosis
- 18 Aug 2026 Active Biotech in collaboration with Icahn School of Medicine and Myeloproliferative Neoplasms Research Consortium plans a preclinical trial for Myelofibrosis in USA
- 24 Jul 2026 EMA approves protocol amendment for phase Ib/II TasqForce trial in Myelofibrosis