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Tasquinimod - Active Biotech

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Drug Profile

Tasquinimod - Active Biotech

Alternative Names: ABR-215050; TASQ

Latest Information Update: 30 Sep 2024

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At a glance

  • Originator Active Biotech
  • Developer Active Biotech; Ipsen; University of Pennsylvania
  • Class Amides; Antineoplastics; Fluorinated hydrocarbons; Quinolines; Small molecules
  • Mechanism of Action Angiogenesis inhibitors; Calgranulin B modulators; Immunomodulators; Thrombospondin 1 agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Multiple myeloma; Myelofibrosis
  • New Molecular Entity Yes
  • Available For Licensing Yes - Multiple myeloma

Highest Development Phases

  • Phase II Myelofibrosis
  • Phase I/II Multiple myeloma
  • Preclinical Myelodysplastic syndromes
  • Discontinued Gastric cancer; Liver cancer; Ovarian cancer; Prostate cancer; Renal cancer

Most Recent Events

  • 20 Sep 2024 Active Biotech plans a phase I/II TasqForce trial for Myelofibrosis (Second-line therapy or greater) in Germany and in the Netherlands in October 2024 (NCT06605586)
  • 30 Aug 2024 Active Biotech plans a phase II proof-of-concept trial for Myelofibrosis in USA in mid 2024 (NCT06327100)
  • 01 Aug 2024 Phase-II clinical trials in Myelofibrosis (Combination therapy) in USA (PO) (NCT06327100)

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