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Drug Profile


Alternative Names: Hepavir B; ICN-2001-3; MB-06866; MB-6866; Pradefovir mesylate; Remofovir; Remofovir mesylate; UNII-GZE85Q9Q61

Latest Information Update: 03 Feb 2016

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At a glance

  • Originator Metabasis Therapeutics
  • Developer Chiva Pharmaceuticals; Ligand Pharmaceuticals; Valeant Pharmaceuticals International
  • Class Adenine nucleotides; Antivirals; Organophosphorus compounds; Purines; Small molecules
  • Mechanism of Action DNA-directed DNA polymerase inhibitors; Hepatitis B virus replication inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Phase III Hepatitis B

Most Recent Events

  • 03 Feb 2016 Pradefovir is in development for Hepatitis B in China
  • 03 Feb 2016 Discontinued - Phase-II for Hepatitis B in USA (PO)
  • 12 Oct 2013 Discontinued - Phase-I for Hepatitis B in Europe (PO)
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