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Drug Profile


Alternative Names: DAB 452; Palindore; SLS-006; WAY-DAB 452

Latest Information Update: 28 Sep 2016

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At a glance

  • Originator Wyeth
  • Developer Ligand Pharmaceuticals; Wyeth
  • Class Antiparkinsonians; Antipsychotics; Indoles; Small molecules
  • Mechanism of Action Dopamine D2 receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Suspended Parkinson's disease; Restless legs syndrome
  • Discontinued Schizophrenia

Most Recent Events

  • 25 Jan 2019 Seelos Therapeutics plans a pivotal registration studies for Parkinson’s disease in 2019
  • 22 Sep 2016 Aplindore sub-licensed to Seelos Therapeutics
  • 31 Dec 2011 Aplindore is available for licensing as of 31 Dec 2011. http://www.ligand.com/
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