AD 4
Alternative Names: L-2-Acetamido-3-mercaptopropionamide; N-Acetylcysteinamide; N-Acetylcysteine amide; AD-4; NACALatest Information Update: 24 Jan 2015
At a glance
- Originator Hebrew University of Jerusalem
- Developer Eucalyptus Ltd; Yissum Research Development Company
- Class Eye disorder therapies; Neuroprotectants; Small molecules; Sulfhydryl compounds
- Mechanism of Action Antioxidants; Chelating agents; Free radical scavengers
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Discontinued Neurodegenerative disorders
Most Recent Events
- 09 Jan 2008 Preclinical trials in Neurodegenerative disorders in USA (PO)
- 09 Jan 2008 AD 4 exclusively licensed to Eucalyptus Ltd. worldwide for the treatment of Neurodegenerative disorders
- 24 Apr 2007 No development reported - Preclinical for Neuroprotection in Israel (PO)