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Research programme: histone deacetylase inhibitors - MethylGene

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Drug Profile

Research programme: histone deacetylase inhibitors - MethylGene

Alternative Names: MG 4230; MG 4915; MG 5026; Next generation inhibitors; Sirtuin inhibitors

Latest Information Update: 25 Jan 2024

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At a glance

  • Originator MethylGene
  • Class Sirtuins; Small molecules
  • Mechanism of Action Histone deacetylase inhibitors; SIRT1 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • No development reported Bacterial infections; Cancer; Diabetes mellitus; Inflammation

Most Recent Events

  • 23 Jan 2024 Mirati Therapeutics has been acquired by Bristol-Myers Squibb
  • 30 Mar 2010 Preclinical development is ongoing in USA
  • 25 Mar 2008 Preclinical development is ongoing

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